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Preparação de fatias do hipocampo aguda de ratos e camundongos transgênicos para o Estudo das Alterações Synaptic durante o envelhecimento e amilóide Patologia
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Preparação de fatias do hipocampo aguda de ratos e camundongos transgênicos para o Estudo das Alterações Synaptic durante o envelhecimento e amilóide Patologia

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14:57 min

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March 23, 2011

DOI:

10.3791/2330-v

DOI:
10.3791/2330-v

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14:57 min
March 23, 2011

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1Graduate Center for Gerontology,University of Kentucky College of Public Health, 2Department of Molecular and Biomedical Pharmacology,University of Kentucky College of Medicine, 3Sanders-Brown Center on Aging,University of Kentucky College of Medicine

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Acute Hippocampal SlicesRatsTransgenic MiceSynaptic AlterationsAgingAmyloid PathologySynaptic FunctionPlasticityElectrophysiological TechniquesCognitive ImpairmentsSynaptic Plasticity MechanismsLong-term PotentiationLong-term DepressionNootropic CompoundsBrain AgingAlzheimer’s Disease (AD)Aged RatsAD Model Mice

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Mathis, D. M., Furman, J. L., Norris, C. M. Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology. J. Vis. Exp. (49), e2330, doi:10.3791/2330 (2011).

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