An Ultrasound-Guided Injection of Therapeutic Drugs into Human Salivary Glands
Published: May 31, 2024
Abstract
Source: Barbero, P., et al, Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea. J. Vis. Exp. (2016)
The video demonstrates an ultrasound-guided injection technique for administering therapeutic drugs into the salivary glands of a human patient.
Protocol
All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board. 1. Procedure BoNT-A preparation NOTE: The abobotulinumtoxinA is a botulinum toxin type A of the Clostridium botulinum complex-hemagglutinin. It is a powder for solution for intramuscular or subcutaneous injection. …
Representative Results
Figure 1: Representation of the Ideal Injection Sites. A) Schematic division of the parotid gland into four quadrants, two cranial and two caudal, for correct injection into four different glandular sites. B) Schematic division of the submandibular gland into one cranial and one caudal quadrant for correct injection into two different glandular sites.
Divulgations
The authors have nothing to disclose.
Materials
| abobotulinumtoxinA (Dysport) | IpsenBiopharm, Wrexham, UK | Delivered drug | |
| MyLab Twice | Esaote | Ultraonograph | |
| LA523 5–10 MHz | Esaote | Linear transducer |
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Citer Cet Article
An Ultrasound-Guided Injection of Therapeutic Drugs into Human Salivary Glands. J. Vis. Exp. (Pending Publication), e22268, doi: (2024).