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Biopharmaceutics and Pharmacokinetics: Overview

JoVE Core
Pharmacokinetics and Pharmacodynamics
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JoVE Core Pharmacokinetics and Pharmacodynamics
Biopharmaceutics and Pharmacokinetics: Overview

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01:28 min

October 10, 2024

Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the appropriate concentration and for a suitable duration. Several influencing factors include the physicochemical properties of the drug, formulation techniques, and the route of administration.

Biopharmaceutics play a fundamental role in the design of drug products. It studies the relationship between the physicochemical properties of a drug and its pharmacological effects. By comprehending biopharmaceutics, scientists can enhance drug delivery, absorption, and bioavailability, ultimately leading to optimized drug formulations.

Pharmacokinetics, on the other hand, deals with the fate of a drug within the body. It involves studying how the body absorbs, distributes, metabolizes, and excretes drugs. Pharmacokinetics provides critical insights from when a drug enters the body to when it is completely eliminated. These insights help determine appropriate dosage regimens and predict drug interactions and potential side effects.

In conclusion, the development and effective use of drugs and drug products rely heavily on understanding their design, performance, and interaction with the body. Biopharmaceutics and pharmacokinetics play essential roles in these processes, contributing significantly to advances in patient care.