Overview
The immune system comprises diverse biological structures and processes that protect the body from disease. These processes can be classified …
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced …
Overview
The ability of a single antibody to recognize multiple structurally similar epitopes is an important immune defense strategy that enables the …
Overview
We speak of an allergy when the immune system triggers a response against a benign foreign structure, like food, pollen or pet dander. These …
Overview
In response to tissue injury and infection, mast cells initiate inflammation. Mast cells release chemicals that increase the permeability of …
Overview
Vaccination is the administration of antigenic material from pathogens to confer immunity against a specific microorganism. Vaccination primes …
Here we describe a method to conditionally induce epithelial cell transformation by the use of the 4-Hydroxytamoxifen (4-OHT) inducible KalTA4-ERT2/UAS …
The enormous upsurge of interest in immune-based treatments for cancer such as vaccines and immune checkpoint inhibitors, and increased understanding of …
A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting in …
The intestinal epithelial barrier separates the host from the microbiota that is normally tolerated or ignored. The breach of this barrier results in the …
