Modeling Small Molecule Ligands in CryoEM Maps of Macromolecules

July 19, 2024

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps

Modeling Phosphoenolpyruvate in Enolase Enzyme from Mycobacterium tuberculosis

Shaileshanand Jha*¹, Sucharita Bose*², Kutti R. Vinothkumar

¹National Centre for Biological Sciences,Tata Institute of Fundamental Research, ²Institute for Stem Cell Science and Regenerative Medicine

Summary

This protocol introduces the tools available for modeling small-molecule ligands in cryoEM maps of macromolecules.

Article