Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Amr Mostafa; Yuya Kanehira; Anushree Dutta; Sergio Kogikoski Jr.; Ilko Bald

doi:10.3791/65310

Single-Molecule SERS Measurements Enabled by Plasmonic DNA Origami Nanoantennas

July 21, 2023

Author Spotlight: Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

02:04 min

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DNA Origami Fork Assembly for DNA Origami Nanoantenna (DONA)

02:21 min

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DNA Coating of Gold Nanoparticle (AuNP) for DNA Origami Nanoantenna (DONA)

02:13 min

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DNA Origami Nanoantenna (DONA) Assembly and Gel Electrophoresis

02:22 min

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Colocalization of AFM and Raman Measurements on DNA Origami Nanoantenna (DONA)

02:14 min

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Amr Mostafa, Yuya Kanehira, Anushree Dutta, Sergio Kogikoski Jr., Ilko Bald

¹Institute of Chemistry,University of Potsdam

Summary

This protocol demonstrates single-molecule surface-enhanced Raman scattering (SERS) measurements using a DNA origami nanoantenna (DONA) combined with colocalized atomic force microscopy (AFM) and Raman measurements.