Sciences du comportement

Validating a Murine Model of Angelman Syndrome Using Behavioral Tests

Validating a Murine Model of Angelman Syndrome Using Behavioral Tests

October 20, 2023

Author Spotlight: A Battery of Highly Reproducible Behavioral Tests to Validate an Angelman Syndrome Murine Model

Elevated Plus Maze Test in an Angelman Syndrome Mouse Model

Open Field Test in an Angelman Syndrome Mouse Model

Tail Suspension Test in an Angelman Syndrome Mouse Model

Gait Analysis in an Angelman Syndrome Mouse Model

Rotarod Test in an Angelman Syndrome Mouse Model

Nestlet Shredding: Nest Building Test in an Angelman Syndrome Mouse Model

Agnieszka Kubik-Zahorodna¹, Jan Prochazka^1,2, Radislav Sedlacek^1,2

¹Czech Centre for Phenogenomics,Institute of Molecular Genetics of the Czech Academy of Sciences, ²Laboratory of Transgenic Models of Diseases,Institute of Molecular Genetics of the Czech Academy of Sciences

Summary

This manuscript presents a set of highly reproducible behavioral tests to validate an Angelman syndrome mouse model.

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