Screening of ?2 Integrin Activation Inhibitors in Human Neutrophils
1Department of Immunology, School of Medicine,UConn Health, 2Center for Molecular Discovery,University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center,University of New Mexico Health Sciences Center, 4Department of Pathology,University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center,University of New Mexico
Summary
Bu protokol, insan nötrofilleri üzerinde β2 integrin aktivasyonunu inhibe eden küçük moleküllü ilaçları tanımlamak için akış sitometrisi tabanlı, yüksek verimli bir tarama yöntemini açıklar.
