Kobayashi Hisataka Molecular Imaging Program National Cancer Institute Biography Publications Institution JoVE Articles Kobayashi Hisataka has not added a biography. If you are Kobayashi Hisataka and would like to personalize this page please email our Author Liaison for assistance. Publications Combination Photoimmunotherapy with Monoclonal Antibodies Recognizing Different Epitopes of Human Epidermal Growth Factor Receptor 2: an Assessment of Phototherapeutic Effect Based on Fluorescence Molecular Imaging Oncotarget. Feb, 2016 | Pubmed ID: 26909859 Comparative Effectiveness of Light Emitting Diodes (LEDs) and Lasers in Near Infrared Photoimmunotherapy Oncotarget. Feb, 2016 | Pubmed ID: 26885688 MR Imaging Biomarkers for Evaluating Therapeutic Effects Shortly After Near Infrared Photoimmunotherapy Oncotarget. Feb, 2016 | Pubmed ID: 26885619 Trastuzumab-Based Photoimmunotherapy Integrated with Viral HER2 Transduction Inhibits Peritoneally Disseminated HER2-Negative Cancer Molecular Cancer Therapeutics. Mar, 2016 | Pubmed ID: 26832799 Molecular Targeted Photoimmunotherapy for HER2-positive Human Gastric Cancer in Combination with Chemotherapy Results in Improved Treatment Outcomes Through Different Cytotoxic Mechanisms BMC Cancer. 2016 | Pubmed ID: 26810644 Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates Bioconjugate Chemistry. Feb, 2016 | Pubmed ID: 26444497 Super Enhanced Permeability and Retention (SUPR) Effects in Tumors Following Near Infrared Photoimmunotherapy Nanoscale. Oct, 2015 | Pubmed ID: 26443992 Near-IR Light-Mediated Cleavage of Antibody-Drug Conjugates Using Cyanine Photocages Angewandte Chemie (International Ed. in English). Nov, 2015 | Pubmed ID: 26403799 Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple Negative Breast Cancer: Optimizing the Conjugate-Light Regimen PloS One. 2015 | Pubmed ID: 26313651 Impact of C4'-O-Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates Molecular Pharmaceutics. Sep, 2015 | Pubmed ID: 26261913 Rapid Intraoperative Visualization of Breast Lesions with γ-glutamyl Hydroxymethyl Rhodamine Green Scientific Reports. 2015 | Pubmed ID: 26165706 Near Infrared Photoimmunotherapy for Lung Metastases Cancer Letters. Aug, 2015 | Pubmed ID: 26021765 Ferumoxytol As an Intraprostatic MR Contrast Agent for Lymph Node Mapping of the Prostate: a Feasibility Study in Non-human Primates Acta Radiologica (Stockholm, Sweden : 1987). May, 2015 | Pubmed ID: 26013022 Near Infrared Photoimmunotherapy Prevents Lung Cancer Metastases in a Murine Model Oncotarget. Aug, 2015 | Pubmed ID: 25992770 Glypican-3 Targeted Human Heavy Chain Antibody As a Drug Carrier for Hepatocellular Carcinoma Therapy Molecular Pharmaceutics. Jun, 2015 | Pubmed ID: 25955255 Photoimmunotherapy of Hepatocellular Carcinoma-targeting Glypican-3 Combined with Nanosized Albumin-bound Paclitaxel Nanomedicine (London, England). 2015 | Pubmed ID: 25929570 Near Infrared Photoimmunotherapy in the Treatment of Pleural Disseminated NSCLC: Preclinical Experience Theranostics. 2015 | Pubmed ID: 25897335 Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Annals of Surgical Oncology. Dec, 2015 | Pubmed ID: 25893411 Selective Cell Elimination in Vitro and in Vivo from Tissues and Tumors Using Antibodies Conjugated with a Near Infrared Phthalocyanine RSC Advances. Mar, 2015 | Pubmed ID: 25866624 Photoimmunotherapy Lowers Recurrence After Pancreatic Cancer Surgery in Orthotopic Nude Mouse Models The Journal of Surgical Research. Jul, 2015 | Pubmed ID: 25799527 Near Infra-red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer PloS One. 2015 | Pubmed ID: 25799218 Sensitive β-galactosidase-targeting Fluorescence Probe for Visualizing Small Peritoneal Metastatic Tumours in Vivo Nature Communications. 2015 | Pubmed ID: 25765713 Magnetic Resonance Sentinel Lymph Node Imaging of the Prostate with Gadofosveset Trisodium-albumin: Preliminary Results in a Canine Model Academic Radiology. May, 2015 | Pubmed ID: 25683498 Viral Transduction of the HER2-extracellular Domain Expands Trastuzumab-based Photoimmunotherapy for HER2-negative Breast Cancer Cells Breast Cancer Research and Treatment. Feb, 2015 | Pubmed ID: 25616354 Photoimmunotherapy Targeting Prostate-specific Membrane Antigen: Are Antibody Fragments As Effective As Antibodies? Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2015 | Pubmed ID: 25500827 Near Infrared Photoimmunotherapy in the Treatment of Disseminated Peritoneal Ovarian Cancer Molecular Cancer Therapeutics. Jan, 2015 | Pubmed ID: 25416790 Preparation and Long-term Biodistribution Studies of a PAMAM Dendrimer G5-Gd-BnDOTA Conjugate for Lymphatic Imaging Nanomedicine (London, England). May, 2015 | Pubmed ID: 25392239 Photoimmunotherapy of Gastric Cancer Peritoneal Carcinomatosis in a Mouse Model PloS One. 2014 | Pubmed ID: 25401794 Cancer Drug Delivery: Considerations in the Rational Design of Nanosized Bioconjugates Bioconjugate Chemistry. Dec, 2014 | Pubmed ID: 25385142 Real-time Monitoring of Hemodynamic Changes in Tumor Vessels During Photoimmunotherapy Using Optical Coherence Tomography Journal of Biomedical Optics. Sep, 2014 | Pubmed ID: 25253195 Analysis of Biodistribution of Intracranially Infused Radiolabeled Interleukin-13 Receptor-targeted Immunotoxin IL-13PE by SPECT/CT in an Orthotopic Mouse Model of Human Glioma Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2014 | Pubmed ID: 24947060 Minibody-indocyanine Green Based Activatable Optical Imaging Probes: the Role of Short Polyethylene Glycol Linkers ACS Medicinal Chemistry Letters. Apr, 2014 | Pubmed ID: 24900850 The Effects of Conjugate and Light Dose on Photo-immunotherapy Induced Cytotoxicity BMC Cancer. 2014 | Pubmed ID: 24885589 Dynamic Fluorescent Imaging with Indocyanine Green for Monitoring the Therapeutic Effects of Photoimmunotherapy Contrast Media & Molecular Imaging. Jul-Aug, 2014 | Pubmed ID: 24706611 Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission PloS One. 2014 | Pubmed ID: 24667371 Photoimmunotherapy: Comparative Effectiveness of Two Monoclonal Antibodies Targeting the Epidermal Growth Factor Receptor Molecular Oncology. May, 2014 | Pubmed ID: 24508062 Magnetic Resonance Lymphography of the Thoracic Duct After Interstitial Injection of Gadofosveset Trisodium: a Pilot Dosing Study in a Porcine Model Lymphatic Research and Biology. Mar, 2014 | Pubmed ID: 24502282 Fluorescence-lifetime Molecular Imaging Can Detect Invisible Peritoneal Ovarian Tumors in Bloody Ascites Cancer Science. Mar, 2014 | Pubmed ID: 24479901 Activatable Organic Near-infrared Fluorescent Probes Based on a Bacteriochlorin Platform: Synthesis and Multicolor in Vivo Imaging with a Single Excitation Bioconjugate Chemistry. Feb, 2014 | Pubmed ID: 24450401 The Effect of Photoimmunotherapy Followed by Liposomal Daunorubicin in a Mixed Tumor Model: a Demonstration of the Super-enhanced Permeability and Retention Effect After Photoimmunotherapy Molecular Cancer Therapeutics. Feb, 2014 | Pubmed ID: 24356818 Dendrimers As High Relaxivity MR Contrast Agents Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Mar-Apr, 2014 | Pubmed ID: 24155241 MR Lymphangiography with Intradermal Gadofosveset and Human Serum Albumin in Mice and Primates Journal of Magnetic Resonance Imaging : JMRI. Sep, 2014 | Pubmed ID: 24123370 Improving Conventional Enhanced Permeability and Retention (EPR) Effects; What is the Appropriate Target? Theranostics. 2013 | Pubmed ID: 24396516 Endoscopic Molecular Imaging of Cancer Future Oncology (London, England). Oct, 2013 | Pubmed ID: 24106901 Improving the Efficacy of Photoimmunotherapy (PIT) Using a Cocktail of Antibody Conjugates in a Multiple Antigen Tumor Model Theranostics. 2013 | Pubmed ID: 23781283 Activatable Fluorescent Cys-diabody Conjugated with Indocyanine Green Derivative: Consideration of Fluorescent Catabolite Kinetics on Molecular Imaging Journal of Biomedical Optics. Oct, 2013 | Pubmed ID: 23752742 Monoclonal Antibody-fluorescent Probe Conjugates for in Vivo Target-specific Cancer Imaging: Toward Clinical Translation Therapeutic Delivery. May, 2013 | Pubmed ID: 23647268 Short PEG-linkers Improve the Performance of Targeted, Activatable Monoclonal Antibody-indocyanine Green Optical Imaging Probes Bioconjugate Chemistry. May, 2013 | Pubmed ID: 23600922 Acute Cytotoxic Effects of Photoimmunotherapy Assessed by 18F-FDG PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2013 | Pubmed ID: 23536226 Optical Imaging of HPV Infection in a Murine Model Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23325640 Polychromatic in Vivo Imaging of Multiple Targets Using Visible and Near Infrared Light Advanced Drug Delivery Reviews. Jul, 2013 | Pubmed ID: 23220327 Markedly Enhanced Permeability and Retention Effects Induced by Photo-immunotherapy of Tumors ACS Nano. Jan, 2013 | Pubmed ID: 23214407 In Vivo Real-time Lymphatic Draining Using Quantum-dot Optical Imaging in Mice Contrast Media & Molecular Imaging. Jan-Feb, 2013 | Pubmed ID: 23109398 Fluorescence Endoscopic Detection of Murine Colitis-associated Colon Cancer by Topically Applied Enzymatically Rapid-activatable Probe Gut. Aug, 2013 | Pubmed ID: 22698650 Gadolinium MRI Contrast Agents Based on Triazine Dendrimers: Relaxivity and In Vivo Pharmacokinetics Bioconjugate Chemistry. Oct, 2012 | Pubmed ID: 23035964 Immediate in Vivo Target-specific Cancer Cell Death After Near Infrared Photoimmunotherapy BMC Cancer. 2012 | Pubmed ID: 22873679 Real-time Monitoring of in Vivo Acute Necrotic Cancer Cell Death Induced by Near Infrared Photoimmunotherapy Using Fluorescence Lifetime Imaging Cancer Research. Sep, 2012 | Pubmed ID: 22800710 Galactosyl Human Serum Albumin-NMP1 Conjugate: a Near Infrared (NIR)-activatable Fluorescence Imaging Agent to Detect Peritoneal Ovarian Cancer Metastases Bioconjugate Chemistry. Aug, 2012 | Pubmed ID: 22799539 The Use of Fluorescent Proteins for Developing Cancer-specific Target Imaging Probes Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22700412 In Vivo Breast Cancer Characterization Imaging Using Two Monoclonal Antibodies Activatably Labeled with Near Infrared Fluorophores Breast Cancer Research : BCR. 2012 | Pubmed ID: 22510481 MR and Optical Imaging of Early Micrometastases in Lymph Nodes: Triple Labeling with Nano-sized Agents Yielding Distinct Signals Contrast Media & Molecular Imaging. Mar-Apr, 2012 | Pubmed ID: 22434638 Near-infrared Theranostic Photoimmunotherapy (PIT): Repeated Exposure of Light Enhances the Effect of Immunoconjugate Bioconjugate Chemistry. Mar, 2012 | Pubmed ID: 22369484 Recipe for a New Imaging Biomarker: Carefully Combine Target, Reagent, and Technology Kidney International. Jan, 2012 | Pubmed ID: 22205431 Quantitative and Specific Molecular Imaging of Cancer with Labeled Engineered Monoclonal Antibody Fragments Therapeutic Delivery. Mar, 2011 | Pubmed ID: 22834005 Rapid Cancer Detection by Topically Spraying a γ-glutamyltranspeptidase-activated Fluorescent Probe Science Translational Medicine. Nov, 2011 | Pubmed ID: 22116934 Cancer Cell-selective in Vivo Near Infrared Photoimmunotherapy Targeting Specific Membrane Molecules Nature Medicine. Dec, 2011 | Pubmed ID: 22057348 Activatable Optical Imaging with a Silica-rhodamine Based Near Infrared (SiR700) Fluorophore: a Comparison with Cyanine Based Dyes Bioconjugate Chemistry. Dec, 2011 | Pubmed ID: 22034863 Molecular Imaging of Tumor Invasion and Metastases: the Role of MRI NMR in Biomedicine. Jul, 2011 | Pubmed ID: 21793070 Targeted, Activatable, in Vivo Fluorescence Imaging of Prostate-specific Membrane Antigen (PSMA) Positive Tumors Using the Quenched Humanized J591 Antibody-indocyanine Green (ICG) Conjugate Bioconjugate Chemistry. Aug, 2011 | Pubmed ID: 21740058 Efficient Access to a Dihydropyran-containing Macrolide Via a Transannular Oxy-Michael Reaction: Total Synthesis of (+)-aspergillide C Chemical Communications (Cambridge, England). Jul, 2011 | Pubmed ID: 21629897 Rational Chemical Design of the Next Generation of Molecular Imaging Probes Based on Physics and Biology: Mixing Modalities, Colors and Signals Chemical Society Reviews. Sep, 2011 | Pubmed ID: 21607237 Dendrimer-based MRI Contrast Agents: the Effects of PEGylation on Relaxivity and Pharmacokinetics Nanomedicine : Nanotechnology, Biology, and Medicine. Dec, 2011 | Pubmed ID: 21515406 Biologically Optimized Nanosized Molecules and Particles: More Than Just Size Bioconjugate Chemistry. Jun, 2011 | Pubmed ID: 21513351 Near Infrared Fluorescence-guided Real-time Endoscopic Detection of Peritoneal Ovarian Cancer Nodules Using Intravenously Injected Indocyanine Green International Journal of Cancer. Oct, 2011 | Pubmed ID: 21469142 In Vivo Longitudinal Imaging of Experimental Human Papillomavirus Infection in Mice with a Multicolor Fluorescence Mini-endoscopy System Cancer Prevention Research (Philadelphia, Pa.). May, 2011 | Pubmed ID: 21430072 Self-illuminating in Vivo Lymphatic Imaging Using a Bioluminescence Resonance Energy Transfer Quantum Dot Nano-particle Contrast Media & Molecular Imaging. Jan-Feb, 2011 | Pubmed ID: 21351373 Target-cancer-cell-specific Activatable Fluorescence Imaging Probes: Rational Design and in Vivo Applications Accounts of Chemical Research. Feb, 2011 | Pubmed ID: 21062101 A Portable Fluorescence Camera for Testing Surgical Specimens in the Operating Room: Description and Early Evaluation Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Oct, 2011 | Pubmed ID: 20960235 Optimizing Quantitative in Vivo Fluorescence Imaging with Near-infrared Quantum Dots Contrast Media & Molecular Imaging. May-Jun, 2011 | Pubmed ID: 20936710 Magnetic Resonance Lymphangiography with a Nano-sized Gadolinium-labeled Dendrimer in Small and Large Animal Models Nanomedicine (London, England). Oct, 2010 | Pubmed ID: 21039196 Biodistribution and Excretion of Monosaccharide-albumin Conjugates Measured with in Vivo Near-infrared Fluorescence Imaging Bioconjugate Chemistry. Oct, 2010 | Pubmed ID: 20853850 Real-time Optical Imaging Using Quantum Dot and Related Nanocrystals Nanomedicine (London, England). Jul, 2010 | Pubmed ID: 20662647 High Sensitivity Detection of Cancer in Vivo Using a Dual-controlled Activation Fluorescent Imaging Probe Based on H-dimer Formation and PH Activation Molecular BioSystems. May, 2010 | Pubmed ID: 20567775 In Vivo Molecular Imaging Using Nanomaterials: General in Vivo Characteristics of Nano-sized Reagents and Applications for Cancer Diagnosis Molecular Membrane Biology. Oct, 2010 | Pubmed ID: 20455640 Multiplexed Imaging in Cancer Diagnosis: Applications and Future Advances The Lancet. Oncology. Jun, 2010 | Pubmed ID: 20338808 New Nanosized Biocompatible MR Contrast Agents Based on Lysine-dendri-graft Macromolecules Bioconjugate Chemistry. May, 2010 | Pubmed ID: 20235572 Two-step Synthesis of Galactosylated Human Serum Albumin As a Targeted Optical Imaging Agent for Peritoneal Carcinomatosis Journal of Medicinal Chemistry. Feb, 2010 | Pubmed ID: 20102220 Fluorescence Lifetime Imaging of Activatable Target Specific Molecular Probes Contrast Media & Molecular Imaging. Jan-Feb, 2010 | Pubmed ID: 20101762 New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging Chemical Reviews. May, 2010 | Pubmed ID: 20000749 Semiquantitative Assessment of the Microdistribution of Fluorescence-labeled Monoclonal Antibody in Small Peritoneal Disseminations of Ovarian Cancer Cancer Science. Mar, 2010 | Pubmed ID: 19961490 Influence of Dendrimer Generation and Polyethylene Glycol Length on the Biodistribution of PEGylated Dendrimers International Journal of Pharmaceutics. Jan, 2010 | Pubmed ID: 19761822 New Approaches to Lymphatic Imaging Lymphatic Research and Biology. Dec, 2009 | Pubmed ID: 20143919 Nanoparticles in Sentinel Lymph Node Mapping Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Nov-Dec, 2009 | Pubmed ID: 20049820 Toxicity of Organic Fluorophores Used in Molecular Imaging: Literature Review Molecular Imaging. Dec, 2009 | Pubmed ID: 20003892 Dual-modality Molecular Imaging Using Antibodies Labeled with Activatable Fluorescence and a Radionuclide for Specific and Quantitative Targeted Cancer Detection Bioconjugate Chemistry. Nov, 2009 | Pubmed ID: 19919110 Clinical Implications of Near-infrared Fluorescence Imaging in Cancer Future Oncology (London, England). Nov, 2009 | Pubmed ID: 19903075 Molecular Probes for the in Vivo Imaging of Cancer Molecular BioSystems. Nov, 2009 | Pubmed ID: 19823742 Fluorophore-quencher Based Activatable Targeted Optical Probes for Detecting in Vivo Cancer Metastases Molecular Pharmaceutics. Mar-Apr, 2009 | Pubmed ID: 19718793 Fluorescence Imaging of Tumors with "smart" PH-activatable Targeted Probes Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19685299 Imaging of Tumor Angiogenesis: Functional or Targeted? AJR. American Journal of Roentgenology. Aug, 2009 | Pubmed ID: 19620425 In Vivo Real-time, Multicolor, Quantum Dot Lymphatic Imaging The Journal of Investigative Dermatology. Dec, 2009 | Pubmed ID: 19536144 In Vivo Stable Tumor-specific Painting in Various Colors Using Dehalogenase-based Protein-tag Fluorescent Ligands Bioconjugate Chemistry. Jul, 2009 | Pubmed ID: 19514716 Multicolor Imaging of Lymphatic Function with Two Nanomaterials: Quantum Dot-labeled Cancer Cells and Dendrimer-based Optical Agents Nanomedicine (London, England). Jun, 2009 | Pubmed ID: 19505244 H-type Dimer Formation of Fluorophores: a Mechanism for Activatable, in Vivo Optical Molecular Imaging ACS Chemical Biology. Jul, 2009 | Pubmed ID: 19480464 Multicolor in Vivo Targeted Imaging to Guide Real-time Surgery of HER2-positive Micrometastases in a Two-tumor Coincident Model of Ovarian Cancer Cancer Science. Jun, 2009 | Pubmed ID: 19302283 Multi-targeted Multi-color in Vivo Optical Imaging in a Model of Disseminated Peritoneal Ovarian Cancer Journal of Biomedical Optics. Jan-Feb, 2009 | Pubmed ID: 19256711 In Vivo Molecular Imaging of Cancer with a Quenching Near-infrared Fluorescent Probe Using Conjugates of Monoclonal Antibodies and Indocyanine Green Cancer Research. Feb, 2009 | Pubmed ID: 19176373 Dendrimers in Medical Nanotechnology IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. Jan-Feb, 2009 | Pubmed ID: 19150767 In Vivo Target-specific Activatable Near-infrared Optical Labeling of Humanized Monoclonal Antibodies Molecular Cancer Therapeutics. Jan, 2009 | Pubmed ID: 19139133 Tumor-specific Detection of an Optically Targeted Antibody Combined with a Quencher-conjugated Neutravidin "quencher-chaser": a Dual "quench and Chase" Strategy to Improve Target to Nontarget Ratios for Molecular Imaging of Cancer Bioconjugate Chemistry. Jan, 2009 | Pubmed ID: 19072537 Selective Molecular Imaging of Viable Cancer Cells with PH-activatable Fluorescence Probes Nature Medicine. Jan, 2009 | Pubmed ID: 19029979 Differentiation of Bacterial and Non-bacterial Community-acquired Pneumonia by Thin-section Computed Tomography European Journal of Radiology. Dec, 2009 | Pubmed ID: 18835120 Dendrimer-based Contrast Agents for Molecular Imaging Current Topics in Medicinal Chemistry. 2008 | Pubmed ID: 18855704 Clearance Properties of Nano-sized Particles and Molecules As Imaging Agents: Considerations and Caveats Nanomedicine (London, England). Oct, 2008 | Pubmed ID: 18817471 Determination of Optimal Rhodamine Fluorophore for in Vivo Optical Imaging Bioconjugate Chemistry. Aug, 2008 | Pubmed ID: 18610943 Multiplexing with Multispectral Imaging: from Mice to Microscopy ILAR Journal / National Research Council, Institute of Laboratory Animal Resources. 2008 | Pubmed ID: 18172335 Multimodal Nanoprobes for Radionuclide and Five-color Near-infrared Optical Lymphatic Imaging ACS Nano. Nov, 2007 | Pubmed ID: 19079788 In Vivo Molecular Imaging to Diagnose and Subtype Tumors Through Receptor-targeted Optically Labeled Monoclonal Antibodies Neoplasia (New York, N.Y.). Dec, 2007 | Pubmed ID: 18084609 [In-vivo Cancer Fluorescence Imaging with Novel Precisely-designed Fluorescence Probes] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Oct, 2007 | Pubmed ID: 18051385 D-galactose Receptor-targeted in Vivo Spectral Fluorescence Imaging of Peritoneal Metastasis Using Galactosamin-conjugated Serum Albumin-rhodamine Green Journal of Biomedical Optics. Sep-Oct, 2007 | Pubmed ID: 17994865 Tumor-targeted Optical Imaging in the Management of Peritoneal Carcinomatosis South Dakota Medicine : the Journal of the South Dakota State Medical Association. Sep, 2007 | Pubmed ID: 17987867 In Vivo Diagnosis of Epidermal Growth Factor Receptor Expression Using Molecular Imaging with a Cocktail of Optically Labeled Monoclonal Antibodies Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2007 | Pubmed ID: 17982120 A Self-quenched Galactosamine-serum Albumin-rhodamineX Conjugate: a "smart" Fluorescent Molecular Imaging Probe Synthesized with Clinically Applicable Material for Detecting Peritoneal Ovarian Cancer Metastases Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2007 | Pubmed ID: 17975145 Targeted Optical Fluorescence Imaging of Human Ovarian Adenocarcinoma Using a Galactosyl Serum Albumin-conjugated Fluorophore Cancer Science. Nov, 2007 | Pubmed ID: 17784874 Preparation and Preliminary Evaluation of a Biotin-targeted, Lectin-targeted Dendrimer-based Probe for Dual-modality Magnetic Resonance and Fluorescence Imaging Bioconjugate Chemistry. Sep-Oct, 2007 | Pubmed ID: 17711320 Reduction of Streptococcus Mutans Adherence and Dental Biofilm Formation by Surface Treatment with Phosphorylated Polyethylene Glycol Antimicrobial Agents and Chemotherapy. Oct, 2007 | Pubmed ID: 17646419 Two-color in Vivo Dynamic Contrast-enhanced Pharmacokinetic Imaging Journal of Biomedical Optics. May-Jun, 2007 | Pubmed ID: 17614724 Toward Improved Syntheses of Dendrimer-based Magnetic Resonance Imaging Contrast Agents: New Bifunctional Diethylenetriaminepentaacetic Acid Ligands and Nonaqueous Conjugation Chemistry Journal of Medicinal Chemistry. Jul, 2007 | Pubmed ID: 17552504 Simultaneous Multicolor Imaging of Five Different Lymphatic Basins Using Quantum Dots Nano Letters. Jun, 2007 | Pubmed ID: 17530812 Two-color Lymphatic Mapping Using Ig-conjugated Near Infrared Optical Probes The Journal of Investigative Dermatology. Oct, 2007 | Pubmed ID: 17522707 Spectral Fluorescence Molecular Imaging of Lung Metastases Targeting HER2/neu Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2007 | Pubmed ID: 17504994 Spectral Near-infrared Fluorescence Imaging of Curved Surfaces Using Projection Reconstruction Algorithms Contrast Media & Molecular Imaging. Mar-Apr, 2007 | Pubmed ID: 17451166 Activatable Fluorescent Molecular Imaging of Peritoneal Metastases Following Pretargeting with a Biotinylated Monoclonal Antibody Cancer Research. Apr, 2007 | Pubmed ID: 17440095 A Target Cell-specific Activatable Fluorescence Probe for in Vivo Molecular Imaging of Cancer Based on a Self-quenched Avidin-rhodamine Conjugate Cancer Research. Mar, 2007 | Pubmed ID: 17363601 An Enzymatically Activated Fluorescence Probe for Targeted Tumor Imaging Journal of the American Chemical Society. Apr, 2007 | Pubmed ID: 17352471 A Dendrimer-based Nanosized Contrast Agent Dual-labeled for Magnetic Resonance and Optical Fluorescence Imaging to Localize the Sentinel Lymph Node in Mice Journal of Magnetic Resonance Imaging : JMRI. Apr, 2007 | Pubmed ID: 17345640 Glucose 1-phosphate Increases Active Transport of Calcium in Intestine Archives of Biochemistry and Biophysics. Apr, 2007 | Pubmed ID: 17320035 [Molecular Imaging; Current Status and Future Prospects in USA] Nihon Rinsho. Japanese Journal of Clinical Medicine. Feb, 2007 | Pubmed ID: 17302262 MR Lymphangiography Using Dendrimer-based Contrast Agents: a Comparison at 1.5T and 3.0T Magnetic Resonance in Medicine. Feb, 2007 | Pubmed ID: 17260373 Small Numbers of Residual Tumor Cells at the Site of Primary Inoculation Are Critical for Anti-tumor Immunity Following Challenge at a Secondary Location Cancer Immunology, Immunotherapy : CII. Jul, 2007 | Pubmed ID: 17139493 Simultaneous Two-color Spectral Fluorescence Lymphangiography with Near Infrared Quantum Dots to Map Two Lymphatic Flows from the Breast and the Upper Extremity Breast Cancer Research and Treatment. May, 2007 | Pubmed ID: 17028977 Imaging of the Lymphatic System: New Horizons Contrast Media & Molecular Imaging. Nov-Dec, 2006 | Pubmed ID: 17191764 A Comparison of the Emission Efficiency of Four Common Green Fluorescence Dyes After Internalization into Cancer Cells Bioconjugate Chemistry. Nov-Dec, 2006 | Pubmed ID: 17105220 Macromolecular MRI Contrast Agents for Imaging Tumor Angiogenesis European Journal of Radiology. Dec, 2006 | Pubmed ID: 16930905 Targeted Optical Imaging of Cancer Cells Using Lectin-binding BODIPY Conjugated Avidin Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16904640 In Vivo Spectral Fluorescence Imaging of Submillimeter Peritoneal Cancer Implants Using a Lectin-targeted Optical Agent Neoplasia (New York, N.Y.). Jul, 2006 | Pubmed ID: 16867223 Dendrimer-based Nanoprobe for Dual Modality Magnetic Resonance and Fluorescence Imaging Nano Letters. Jul, 2006 | Pubmed ID: 16834429 Imaging Acute Renal Failure with Polyamine Dendrimer-based MRI Contrast Agents Nephron. Clinical Practice. 2006 | Pubmed ID: 16543755 Delivery of Gadolinium-labeled Nanoparticles to the Sentinel Lymph Node: Comparison of the Sentinel Node Visualization and Estimations of Intra-nodal Gadolinium Concentration by the Magnetic Resonance Imaging Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2006 | Pubmed ID: 16490277 Detection of Lymph Node Involvement in Hematologic Malignancies Using Micromagnetic Resonance Lymphangiography with a Gadolinum-labeled Dendrimer Nanoparticle Neoplasia (New York, N.Y.). Nov, 2005 | Pubmed ID: 16331884 Nano-sized MRI Contrast Agents with Dendrimer Cores Advanced Drug Delivery Reviews. Dec, 2005 | Pubmed ID: 16290152 Dendrimer-enhanced MRI As a Diagnostic and Prognostic Biomarker of Sepsis-induced Acute Renal Failure in Aged Mice Kidney International. Jun, 2005 | Pubmed ID: 15882259 Posterior Cul-de-sac Obliteration Associated with Endometriosis: MR Imaging Evaluation Radiology. Mar, 2005 | Pubmed ID: 15665220 Lymphatic Dysfunction in Transgenic Mice Expressing KSHV K-cyclin Under the Control of the VEGFR-3 Promoter Blood. Mar, 2005 | Pubmed ID: 15536152 Role of Trans-cellular IL-15 Presentation in the Activation of NK Cell-mediated Killing, Which Leads to Enhanced Tumor Immunosurveillance Blood. Jan, 2005 | Pubmed ID: 15367431 Dendrimer-based Nanosized MRI Contrast Agents Current Pharmaceutical Biotechnology. Dec, 2004 | Pubmed ID: 15579043 Application of a Macromolecular Contrast Agent for Detection of Alterations of Tumor Vessel Permeability Induced by Radiation Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2004 | Pubmed ID: 15570005 Polyamine Dendrimer-based MRI Contrast Agents for Functional Kidney Imaging to Diagnose Acute Renal Failure Journal of Magnetic Resonance Imaging : JMRI. Sep, 2004 | Pubmed ID: 15332261 Lymphatic Drainage Imaging of Breast Cancer in Mice by Micro-magnetic Resonance Lymphangiography Using a Nano-size Paramagnetic Contrast Agent Journal of the National Cancer Institute. May, 2004 | Pubmed ID: 15126607 Micro-MRI Methods to Detect Renal Cysts in Mice Kidney International. Apr, 2004 | Pubmed ID: 15086495 Hepatocyte Targeting of 111In-labeled Oligo-DNA with Avidin or Avidin-dendrimer Complex Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2004 | Pubmed ID: 15013240 Herceptin-geldanamycin Immunoconjugates: Pharmacokinetics, Biodistribution, and Enhanced Antitumor Activity Cancer Research. Feb, 2004 | Pubmed ID: 14973048 Uterine Peristalsis Shown on Cine MR Imaging Using Ultrafast Sequence Journal of Magnetic Resonance Imaging : JMRI. Dec, 2003 | Pubmed ID: 14635158 Comparison of Dendrimer-based Macromolecular Contrast Agents for Dynamic Micro-magnetic Resonance Lymphangiography Magnetic Resonance in Medicine. Oct, 2003 | Pubmed ID: 14523962 Radiolabeling of Avidin with Very High Specific Activity for Internal Radiation Therapy of Intraperitoneally Disseminated Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003 | Pubmed ID: 14506168 Activated Clearance of a Biotinylated Macromolecular MRI Contrast Agent from the Blood Pool Using an Avidin Chase Bioconjugate Chemistry. Sep-Oct, 2003 | Pubmed ID: 13129410 Optimal Scan Time for Evaluating Pancreatic Disease with Positron Emission Tomography Using F-18-fluorodeoxyglucose Annals of Nuclear Medicine. Jul, 2003 | Pubmed ID: 12971645 Dendrimer-based Macromolecular MRI Contrast Agents: Characteristics and Application Molecular Imaging. Jan, 2003 | Pubmed ID: 12926232 Inflammatory Breast Cancer: Vasculogenic Mimicry and Its Hemodynamics of an Inflammatory Breast Cancer Xenograft Model Breast Cancer Research : BCR. 2003 | Pubmed ID: 12793894 Detection of Inflammation Following Renal Ischemia by Magnetic Resonance Imaging Kidney International. Jul, 2003 | Pubmed ID: 12787394 Differential Uptake of (18)F-fluorodeoxyglucose by Experimental Tumors Xenografted into Immunocompetent and Immunodeficient Mice and the Effect of Immunomodification Neoplasia (New York, N.Y.). Mar-Apr, 2003 | Pubmed ID: 12659691 Macromolecular MRI Contrast Agents with Small Dendrimers: Pharmacokinetic Differences Between Sizes and Cores Bioconjugate Chemistry. Mar-Apr, 2003 | Pubmed ID: 12643749 Micro-magnetic Resonance Lymphangiography in Mice Using a Novel Dendrimer-based Magnetic Resonance Imaging Contrast Agent Cancer Research. Jan, 2003 | Pubmed ID: 12543772 Lowering of PI by Acylation Improves the Renal Uptake of 99mTc-labeled Anti-Tac DsFv: Effect of Different Acylating Reagents Nuclear Medicine and Biology. Nov, 2002 | Pubmed ID: 12453588 Dynamic Micro-MRI of Liver Micrometastasis with a Novel Liver Macromolecular MR Contrast Agent DAB-Am64-(1B4M-Gd)64 Academic Radiology. Aug, 2002 | Pubmed ID: 12188305 Modifications in Synthesis Strategy Improve the Yield and Efficacy of Geldanamycin-herceptin Immunoconjugates Bioconjugate Chemistry. Jul-Aug, 2002 | Pubmed ID: 12121134 Renal Tubular Damage Detected by Dynamic Micro-MRI with a Dendrimer-based Magnetic Resonance Contrast Agent Kidney International. Jun, 2002 | Pubmed ID: 12028438 Increased (18)F-FDG Uptake in a Model of Inflammation: Concanavalin A-mediated Lymphocyte Activation Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2002 | Pubmed ID: 11994531 Rapid Accumulation and Internalization of Radiolabeled Herceptin in an Inflammatory Breast Cancer Xenograft with Vasculogenic Mimicry Predicted by the Contrast-enhanced Dynamic MRI with the Macromolecular Contrast Agent G6-(1B4M-Gd)(256) Cancer Research. Feb, 2002 | Pubmed ID: 11830544 Improved Renal Clearance and Tumor Targeting of 99mTc-labeled Anti-Tac Monoclonal Antibody Fab by Chemical Modifications Nuclear Medicine and Biology. Feb, 2002 | Pubmed ID: 11823118 Hemodynamics in Vasculogenic Mimicry and Angiogenesis of Inflammatory Breast Cancer Xenograft Cancer Research. Jan, 2002 | Pubmed ID: 11809710 Selective Cell Elimination from Mixed 3D Culture Using a Near Infrared Photoimmunotherapy Technique Kazuhide Sato1, Peter L. Choyke1, Kobayashi Hisataka1 1Molecular Imaging Program, National Cancer Institute JoVE 53633 Bio-ingénierie
Selective Cell Elimination from Mixed 3D Culture Using a Near Infrared Photoimmunotherapy Technique Kazuhide Sato1, Peter L. Choyke1, Kobayashi Hisataka1 1Molecular Imaging Program, National Cancer Institute JoVE 53633 Bio-ingénierie