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Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model
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En murin model af hyperlipidæmi-induceret hjertesvigt med bevaret ejektionsfraktion
JoVE Revista
Medicina
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JoVE Revista Medicina
A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction

En murin model af hyperlipidæmi-induceret hjertesvigt med bevaret ejektionsfraktion

Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model

DOI:
10.3791/66442-v

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01:59 min

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March 29, 2024

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, , , , , , , ,
1Department of Medicine, Division of Cardiology,University of Miami Leonard M. Miller School of Medicine, 2Interdisciplinary Stem Cell Institute,University of Miami Leonard M. Miller School of Medicine, 3Department of Molecular and Cellular Pharmacology,University of Miami Leonard M. Miller School of Medicine, 4Department of Medical Education,University of Miami Leonard M. Miller School of Medicine

Tags

HyperlipidemiaHeart Failure With Preserved Ejection Fraction (HFpEF)Murine ModelPoloxamer-407 (P-407)Adeno-associated Virus 9-cardiac Troponin T-low-density Lipoprotein Receptor (AAV9-cTnT-LDLR)Diastolic DysfunctionCardiac IschemiaMetabolic SyndromeLipotoxicity

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