Journal
/
Inmunología y contagio
/
En musemodel af kronisk leverfibrose til undersøgelse af galde atresi
JoVE Revista
Inmunología y contagio
This content is Free Access.
JoVE Revista Inmunología y contagio
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

En musemodel af kronisk leverfibrose til undersøgelse af galde atresi

DOI:
10.3791/65044-v

•

09:12 min

•

February 03, 2023

•

, , , ,
1School of Medicine,South China University of Technology, 2Provincial Key Laboratory of Research in Structure Birth Defect Disease and Department of Pediatric Surgery,Guangzhou Women and Children’s Medical Center

Capítulos

  • 00:04Introduction
  • 00:50Establishment of the Chronic Fibrotic BA Mouse Model
  • 01:45Intraperitoneal Injection of the Mice
  • 02:36Collection of Sample Tissue
  • 03:13Fluorescein Angiography of the Extrahepatic Bile Duct
  • 03:41H&E Staining
  • 04:43CK19 and F4/80 Immunohistochemical Staining
  • 06:00Sirius Red Staining
  • 06:55Results: Effects of Anti‐Ly6G Antibody Treatment in a Mouse Model of Biliary Atresia (BA) Infected with RRV
  • 08:42Conclusion

Summary

Traducción Automática

Traducción Automática

Vi etablerede en musemodel for kronisk leverfibrose, som giver en passende dyremodel til det virusinducerede leverfibrose mekanistiske studie af galdeatresi (BA) og en platform for fremtidige BA-behandlinger.

Tags

Mouse ModelChronic Liver FibrosisBiliary AtresiaRhesus RotavirusAnti-Ly6G AntibodyIntraperitoneal InjectionLiver FunctionFluorescent DyeGallbladderExtrahepatic Bile Ducts

Article

Embed

Añadir a la lista de reproducción

Usage Statistics

Videos relacionados

Introducing Shear Stress in the Study of Bacterial Adhesion

Kutan leishmaniasis i den dorsale hud af hamstere: en nyttig model til screening af Antileishmanial Drugs

Langtids kronisk<em> Pseudomonas aeruginosa</em> Luftvejsinfektion i mus

En Flow Vedhæftning Assay til at studere Leucocyte Rekruttering til human hepatiske Sinusformede endotel Under betingelser for forskydningsspænding

En mus Model for Patogen-induceret kronisk inflammation på lokale og systemiske websteder

En IL-8 Transient Transgenized Mouse Model for<em> In vivo</em> Langsigtet overvågning af inflammatoriske reaktioner

To-foton Intravital billeddannelse af leukocytter under immunrespons i LPS-behandlede mus lever

En sølv nanopartikler metode til mildne biliær atresi syndrom i mus

Fordøjelsen af Murine leveren en Flow Cytometric analyse af lymfatisk Endothelial Cells

Etablering af Dual humaniseret TK-NOG muse model for HIV-associeret lever patogenesen

Read Article