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用于慢性病大型哺乳动物心脏模型对比增强显影显微计算机断层扫描的组织制备技术

JoVE Revista
Medicina

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JoVE Revista Medicina

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease

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用于慢性病大型哺乳动物心脏模型对比增强显影显微计算机断层扫描的组织制备技术

2,096 Views

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12:15 min

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February 08, 2022

DOI:

10.3791/62909-v

DOI:

10.3791/62909-v

•

12:15 min

February 08, 2022

•

4 Views

Néstor Pallares-Lupon^1,2, Jason D. Bayer^1,2, Bastien Guillot^1,2, Guido Caluori^1,2, Girish S. Ramlugun^1,2, Kanchan Kulkarni^1,2, Virginie Loyer^1,2, Stephane Bloquet^1,2, Dounia El Hamrani^1,2, Jérôme Naulin^1,2, Marion Constantin^1,2, Pierre Dos Santos^1,2,3, Olivier Bernus^1,2, Pierre Jaïs^1,2,3, Philippe Pasdois^1,2, Richard D. Walton^1,2

¹Centre de recherche Cardio-Thoracique de Bordeaux,Univ. Bordeaux, ²IHU Liryc, Electrophysiology and Heart Modeling Institute,Fondation Bordeaux Univ., ³Electrophysiology and Ablation Unit,Bordeaux University Hospital (CHU)

Summary

在这里，我们提出了一种方案，以获得健康和病理性的大型哺乳动物全心的高分辨率微计算机断层扫描图像，并具有胶原选择性对比度增强。

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