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JoVE Journal Developmental Biology

用于微CT成像的成人和早期产后小鼠肺的血管铸造

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用于微CT成像的成人和早期产后小鼠肺的血管铸造

Article DOI: 10.3791/61242-v • 09:00 min • June 20th, 2020

June 20th, 2020 •

Russell H. Knutsen¹, Leah M. Gober¹, Joseph R. Sukinik¹, Danielle R. Donahue², Elise K. Kronquist¹, Mark D. Levin¹, Sean E. McLean³, Beth A. Kozel¹

¹Translational Vascular Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health, ²Mouse Imaging Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, ³Division of Pediatric Surgery, Department of Surgery, University of North Carolina at Chapel Hill

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该技术的目的是通过肺膨胀和通过肺动脉注射放射性不透明聚合物化合物，对早期产后小鼠和成年小鼠的肺动脉网络进行活体可视化。还讨论了铸造组织的潜在应用。

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发育生物学，问题 160，肺，微计算断层扫描，灌注，血管，动脉，成像，铸造

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