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Biochemistry

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JoVE Journal Biochemistry
Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging
 

Characterization of Amyloid Structures in Aging C. Elegans Using Fluorescence Lifetime Imaging

Article DOI: 10.3791/61004-v • 09:31 min • March 27th, 2020
March 27th, 2020 •
*1,2, *1, *1, 3, 1,4
1Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin, 2NeuroCure Cluster of Excellence, Charité - Universitätsmedizin Berlin, 3Molecular Neuroscience Group, Department of Chemical Engineering and Biotechnology, University of Cambridge, 4Cell Biology, University of Bremen
* These authors contributed equally

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Fluorescence lifetime imaging monitors, quantifies and distinguishes the aggregation tendencies of proteins in living, aging, and stressed C. elegans disease models.

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Keywords: Amyloid Structures Fluorescence Lifetime Imaging Protein Aggregation C. Elegans Neurodegenerative Diseases FLIM Agarose Pads Nematodes
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