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Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
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Medicina
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JoVE Revista Medicina
Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

7,319 Views

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08:39 min

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November 07, 2020

DOI:

10.3791/60628-v

DOI:
10.3791/60628-v

•

08:39 min
November 07, 2020

•

16 Views
, , , , , , , , , , , ,
1Multi-Organ Transplant Program,University Health Network, 2Department of Immunology,University of Toronto, 3Department of Laboratory Medicine and Pathobiology,University of Toronto

Summary

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The goal of this study is to modify the rat orthotopic liver transplant model to better represent human liver transplantation and improve recipient survival. The presented method reestablishes hepatic arterial inflow by connecting the donor liver's common hepatic artery to the recipient liver's proper hepatic artery.

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Rat Orthotopic Liver TransplantationLiver Transplantation ModelArterial ReconnectionReduced ComplicationsMicrosurgeryBile Duct StentHepatic ArteryPortal VeinDonor LiverRecipient Survival

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Chen, X., Sekhon, M., Ma, X., Manuel, J., Chung, S., He, E., Bartczak, A., Fischer, S., Thoeni, C., Oldani, G., Perciani, C. T., MacParland, S., McGilvray, I. Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation. J. Vis. Exp. (165), e60628, doi:10.3791/60628 (2020).

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