This protocol details how to implement and perform multi-fiber photometry recordings, how to correct for calcium-independent artifacts, and important considerations for dual-color photometry imaging.
Martianova, E., Aronson, S., Proulx, C. D. Multi-Fiber Photometry to Record Neural Activity in Freely-Moving Animals. J. Vis. Exp. (152), e60278, doi:10.3791/60278 (2019).