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Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
JoVE Revista
Quimica
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JoVE Revista Quimica
Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds

Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds

DOI:
10.3791/60021-v

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09:44 min

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October 15, 2019

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, , , , ,
1Department of Biomolecular Science, Faculty of Science,Toho University

Capítulos

  • 00:04Título
  • 00:57Clickable Caged Amine Preparation
  • 01:53Functional Unit Installation
  • 03:12Quantum Efficiency Measurements at 350 nm
  • 03:59HaloTag Ligand Targeting
  • 06:28Photomediated Kinase Localization Modulation
  • 07:33Results: Physical, Photochemical, and Functional Properties of Clickable Caged Compounds
  • 09:05Conclusion

Summary

Traducción Automática

Traducción Automática

A protocol for the synthesis and measurement of the photochemical properties of modular caged compounds with clickable moieties is presented.

Tags

Clickable Caged CompoundsPhotocaged CompoundsWater SolubilityCellular TargetingPhotosensitivityPaBhcN-carbonyldiimidazole4-DimethylaminopyridineTert-butyl 6-amino Hexyl CarbamateCopper SulfateTris(3-hydroxypropyltriazolylmethyl)amineSodium-l-ascorbate15-chloro-369-trioxypentyldecyl AzideHPLCQuantum Efficiency

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