This protocol describes a new method to estimate the number of functioning motor units in a muscle, by fitting a model to a detailed stimulus-response curve of the compound muscle action potential. It is quick and easy to perform and analyze and has excellent reproducibility.
Jacobsen, A. B., Bostock, H., Tankisi, H. CMAP Scan MUNE (MScan) - A Novel Motor Unit Number Estimation (MUNE) Method. J. Vis. Exp. (136), e56805, doi:10.3791/56805 (2018).