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Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping
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Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping

9,431 Views

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08:19 min

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February 22, 2018

DOI:

10.3791/56478-v

DOI:
10.3791/56478-v

•

08:19 min
February 22, 2018

•

15 Views
, , , , ,
1Department of Bio-informational Pharmacology, Medical Research Institute,Tokyo Medical and Dental University, 2Department of Biofunctional Informatics,Tokyo Medical and Dental University

Summary

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This protocol describes the electrophysiological evaluation of murine atria utilizing an optical mapping system with a high temporal and spatial resolution, including dual recordings of the membrane voltage and Ca2+ transient under programmed stimulation through a specialized electrode catheter.

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Ihara, K., Sugiyama, K., Takahashi, K., Yamazoe, M., Sasano, T., Furukawa, T. Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping. J. Vis. Exp. (132), e56478, doi:10.3791/56478 (2018).

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