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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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October 24, 2017
DOI:
1Devision of Repreoductive Endocrinology and Infertility, Department of Obstetrics and Gynecology,Baylor College of Medicine, 2Mouse Phenotyping Core,Baylor College of Medicine, 3Reproductive and Developmental Biology Laboratory,National Institute of Environmental Health Sciences, 4Department of Molecular and Cellular Biology,Baylor College of Medicine
Summary
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Mice are widely used to study gestational biology. However, pregnancy termination is required for such studies which precludes longitudinal investigations and necessitates the use of large numbers of animals. Therefore, we describe a non-invasive technique of high-frequency ultrasonography for early detection and monitoring of post-implantation events in the pregnant mouse.
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Peavey, M. C., Reynolds, C. L., Szwarc, M. M., Gibbons, W. E., Valdes, C. T., DeMayo, F. J., Lydon, J. P. A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse. J. Vis. Exp. (128), e56207, doi:10.3791/56207 (2017).
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