/
/
Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.
Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
8,639 Views
•
08:43 min
•
June 06, 2016
DOI:
1Department of Nanobiomedical Sciences and BK21 PLUS NBM Global Research Center for Regenerative Medicine,Dankook University, 2Insititute of Tissue Regeneration Engineering,Dankook University, 3Department of Biological Sciences,Ajou University, 4Department of Pharmacy,Sahmyook University, 5Department of Animal Biotechnology,Sahmyook University
Summary
Automatically generated
The goal of this protocol is to describe a loss- and gain-of function method that is applicable to identify neogenin as a stage-specific receptor that leads to trophectoderm and inner cell mass differentiation in preimplantation mouse embryos.
Explore More Videos
Read Article
Cite this Article
Lee, J. H., Cho, Y. I., Choi, S. S., Kim, H., Min, C. K., Lee, S. J. Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos. J. Vis. Exp. (112), e53696, doi:10.3791/53696 (2016).
Copy