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接口3D工程神经细胞微电极阵列：一种创新<em>体外</em>实验模型
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JoVE Revista Neurociencias
Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
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接口3D工程神经细胞微电极阵列：一种创新<em>体外</em>实验模型

9,846 Views

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09:47 min

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October 18, 2015

DOI:

10.3791/53080-v

DOI:
10.3791/53080-v

•

09:47 min
October 18, 2015

•

4 Views
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1Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS),University of Genova, 2Donders Institute for Brain, Cognition and Behaviour, Department of Cognitive Neuroscience,Radboud University Medical Center, 3Fondazione Istituto Italiano di Tecnologia (IIT)

Summary

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In this work, a novel experimental model in which 3D neuronal cultures are coupled to planar Micro-Electrode Arrays (MEAs) is presented. 3D networks are built by seeding neurons in a scaffold made up of glass microbeads on which neurons grow and form interconnected 3D structures.

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Cite this Article

Tedesco, M., Frega, M., Martinoia, S., Pesce, M., Massobrio, P. Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model. J. Vis. Exp. (104), e53080, doi:10.3791/53080 (2015).

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