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JoVE Journal Developmental Biology
Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals
 

Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals

Article DOI: 10.3791/52768-v • 07:07 min • July 10th, 2015
July 10th, 2015 •
1,2, 1,3, 1, 1, 3, 3, 3
1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, 3Department of Molecular and Cellular Sports Medicine, German Sports University Cologne

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Investigation of early endothelial cell (EEC) migration is important to understand the pathophysiology of certain illnesses and to potentially identify novel strategies for therapeutic intervention. The following protocol describes techniques to assess cell migration that have been adapted for the investigation of EEC.

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Keywords: Endothelial Cell Migration Toxic Chemicals Wound Healing Chemical Warfare Agents Sulfur Mustard Nitrogen Mustard Vasculogenesis Angiogenesis Boyden Chamber Wound Healing Assay Track Analysis TMRM Mitochondrial Membrane Potential
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