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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
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December 27, 2013
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We describe the production and characterization of nanoparticles and microparticles composed of poly(lactic-co-glycolic acid) using vitamin E-TPGS as an emulsifier. By varying formulation parameters such as the concentration of emulsifier, it is possible to produce nanoparticles with mean diameters ranging from 220 nm to 1.98 µm.
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McCall, R. L., Sirianni, R. W. PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS. J. Vis. Exp. (82), e51015, doi:10.3791/51015 (2013).
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