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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
Chapters
- 00:05Title
- 01:38Nanoparticle Preparation
- 06:23Nanoparticle Collection
- 09:07Sizing and Surface Morphology Using Scanning Electron Microscopy
- 10:43Results: Particle Size Is Dependent on Emulsifier Concentration
- 12:15Conclusion
We describe the production and characterization of nanoparticles and microparticles composed of poly(lactic-co-glycolic acid) using vitamin E-TPGS as an emulsifier. By varying formulation parameters such as the concentration of emulsifier, it is possible to produce nanoparticles with mean diameters ranging from 220 nm to 1.98 µm.
