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Capítulos
- 00:05Título
- 01:11Seeding of Endothelial Cells and Cell Differentiation
- 02:50Stretch-induced Injury of Endothelial Cells
- 03:46Assessment of Stretch Injury by Dye Uptake Assay and Lactate Dehydrogenase Release
- 05:20Results: Stretch in Brain Microvascular Endothelial Cells as an In Vitro Traumatic Brain Injury Model of the Blood Brain Barrier
- 06:50Conclusion
In vitro traumatisk hjerneskade modeller er under udvikling til at gengive in vivo hjerne deformation. Stretch-induceret skade har været ansat i astrocytter, neuroner, gliaceller, aorta og hjerne endotelceller. Men vores system anvender en blod-hjerne barrieren (BBB) model, der besidder egenskaber, der udgør en legitim model af BBB til at etablere en in vitro TBI model.
