This content is Free Access.
A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
1Institute of Medical Microbiology and Hygiene,University of Lübeck, 2Institute of Anatomie,University of Lübeck, 3Department of Obstetrics and Gynecology, University Hospital of Schleswig-Holstein,University of Lübeck, 4Medical Clinic III, University Hospital of Schleswig-Holstein,University of Lübeck
Capítulos
- 00:05Título
- 02:07Preparation and Infection of Human Fallopian Tubes
- 04:08Preparation of Human Fallopian Tube Specimens for Transmission Electron Microscopy
- 05:47Preparation of Human Fallopian Tube Specimens for Scanning Electron Microscopy
- 07:00Results/Discussion
We describe an ex vivo infection model for visualisation of direct interactions from bacterial pathogens with human fallopian tube cells. The whole organ tissue model was established to investigate C. trachomatis induced pathology to the female fallopian tube under "life-like" conditions.
Tags
C. TrachomatisGenital Tract InfectionsAscending InfectionsChronic Inflammatory DamagePelvic Inflammatory Disease (PID)Tubal OcclusionInfertilityEpithelial Cell LinesHEp-2 CellsHeLa-229MicePathophysiologySignaling CascadesIFN-γ Mediated JAK/STAT Signaling PathwayWhole Organ Fallopian Tube ModelHuman Fallopian Tube CellsEx VivoSerovar DScanning Electron Microscopy (SEM)Transmission Electron Microscopy
