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Generation of Mice Derived from Induced Pluripotent Stem Cells
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Generation of Mice Derived from Induced Pluripotent Stem Cells

Generation of Mice Derived from Induced Pluripotent Stem Cells

20,885 Views

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11:56 min

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November 29, 2012

DOI:

10.3791/4003-v

DOI:
10.3791/4003-v

•

11:56 min
November 29, 2012

•

7 Views
, , , , , ,
1Dorris Neuroscience Center & Department of Cell Biology,The Scripps Research Institute , 2Mouse Genetics Core Facility,The Scripps Research Institute

Summary

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Generating induced pluripotent stem cell (iPSC) lines produces lines of differing developmental potential even when they pass standard tests for pluripotency. Here we describe a protocol to produce mice derived entirely from iPSCs, which defines the iPSC lines as possessing full pluripotency1.

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Cite this Article

Boland, M. J., Hazen, J. L., Nazor, K. L., Rodriguez, A. R., Martin, G., Kupriyanov, S., Baldwin, K. K. Generation of Mice Derived from Induced Pluripotent Stem Cells. J. Vis. Exp. (69), e4003, doi:10.3791/4003 (2012).

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