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手術標本の腫瘍外植片を用いて新規抗がん薬の開発のための方法

JoVE Revista
Medicina

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JoVE Revista Medicina

Method for Novel Anti-Cancer Drug Development using Tumor Explants of Surgical Specimens

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手術標本の腫瘍外植片を用いて新規抗がん薬の開発のための方法

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09:26 min

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July 29, 2011

DOI:

DOI:

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09:26 min

July 29, 2011

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Kaushal Joshi, Habibe Demir, Ryosuke Yamada, Takeshi Miyazaki, Abhik Ray-Chaudhury, Ichiro Nakano

¹Department of Neurological Surgery,The Ohio State University Medical Center, ²Department of Pathology,The Ohio State University Medical Center

Tags

Novel Anti-cancer Drug Development Tumor Explants Surgical Specimens Malignant Glioma Drug Efficacy Tests Pre-clinical Phase In Vitro Culture Cell Lines Phenotypic Alterations Genetic Alterations Epigenetic Alterations Xenograft Models Immunodeficient Mice Microenvironment Undissociated Tumor Blocks Treatment Effects Evaluation Temozolomide (TMZ)Intratumoral Injection Drug Candidates Analysis

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