Measuring the Electrophysiological Activity of Neuronal Networks Using Micro-Electrode Arrays

Acquire the data at 1,200 times amplification and sample the signal at 10 kilohertz using the MCS data acquisition card. Record 20 minutes of electrophysiological activity of hiPSC-derived neurons cultured on MEAs. During the recording, maintain the temperature at 37 degrees Celcius and prevent medium evaporation and pH changes by delivering a constant slow flow of humidified gas onto the MEAs. After that, analyze the data using a custom software package.