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21.15:

Anatomy of the Adrenal Glands

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Anatomy and Physiology
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JoVE Central Anatomy and Physiology
Anatomy of the Adrenal Glands

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The adrenal or supra-renal glands are paired, pyramid-shaped glands located above the kidney and in line with the twelfth rib.  When the body experiences stress, these glands respond by secreting hormones. The synthesis of these hormones requires stored cholesterol and fatty acids which give the glands a yellow tinge. A fibrous capsule and fat cushion these glands. The adrenal gland contains two regions, each with distinct functions. The adrenal cortex is the outer layer that forms the bulk of the gland and synthesizes hormones such as corticosteroids that promote long-lasting responses to stress. It contains three lipid-laden cell layers: the zona glomerulosa, the top layer; the zona fasciculata, the middle layer; and the zona reticularis, the innermost layer.   The adrenal medulla is the interior layer that is encapsulated by the cortex. It is composed of nervous tissue and contains spherical chromaffin cells surrounding capillaries. Chromaffin cells synthesize catecholamines, hormones that promote more immediate and brief effects, such as the fight-or-flight response.

21.15:

Anatomy of the Adrenal Glands

The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.

These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.

The adrenal gland comprises two distinct regions with specialized functions. The outer layer, the adrenal cortex, constitutes most of the gland and synthesizes corticosteroids. These hormones produced by the zona glomerulosa, zona fasciculata, and zona reticularis regions facilitate prolonged responses to stress.

Encapsulated by the cortex, the interior layer is the adrenal medulla, composed of nervous tissue. This region houses spherical chromaffin cells surrounding capillaries. Chromaffin cells play a pivotal role in synthesizing catecholamines, such as adrenaline and noradrenaline. These hormones induce immediate and brief effects, precipitating the well-known fight-or-flight response during stressful situations.

In summary, the adrenal glands are crucial in orchestrating both immediate and protracted physiological responses to stress, ensuring the body's adaptability and survival in challenging situations.