JOVE JOURNAL

Investigación sobre el cáncer

Showing 289 - 300 in 611 videos.

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

David Jelinek^1,2, Ellen Ran Zhang^1,2,3, Aaron Ambrus^1,2, Erin Haley³, Emily Guinn^1,2, Austin Vo^1,2, Peter Le^1,2, Ayse Elif Kesaf^1,2, Jennifer Nguyen^1,2, Lily Guo^1,2, Destiny Frederick^1,2, Zhengyang Sun^1,2, Natalie Guo³, Parker Sevier^1,2, Eric Bilotta^1,2, Kaiser Atai^1,2,4, Laurent Voisin^1,2, Hilary A. Coller^1,2,4

¹Department of Molecular, Cell and Developmental Biology,University of California, Los Angeles, ²Department of Biological Chemistry, David Geffen School of Medicine,University of California, Los Angeles, ³Department of Molecular Biology,Princeton University, ⁴Molecular Biology Institute,University of California, Los Angeles

Journal (Cancer Research)

Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform

Lindsey K. Sablatura¹, Kristin M. Bircsak², Peter Shepherd³, Karla Queiroz⁴, Mary C. Farach-Carson^1,5,6, Pamela E. Constantinou^1,7, Anthony Saleh², Nora Navone³, Daniel A. Harrington^1,5,6

¹Department of BioSciences,Rice University, ²Mimetas US Inc, ³Department of Genitourinary Medical Oncology Research, Division of Cancer Medicine,The University of Texas MD Anderson Cancer Center, ⁴Mimetas B.V., ⁵Department of Bioengineering,Rice University, ⁶Department of Diagnostic and Biomedical Sciences,The University of Texas Health Science Center, ⁷Sheikh Ahmed Center for Pancreatic Cancer Research,The University of Texas MD Anderson Cancer Center

Journal (Cancer Research)

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Kristin M. Riching¹, Sarah D. Mahan¹, Marjeta Urh¹, Danette L. Daniels¹

¹Promega Corporation

Journal (Cancer Research)

Isolation of Proximal Fluids to Investigate the Tumor Microenvironment of Pancreatic Adenocarcinoma

Greta Donisi*¹, Marialuisa Barbagallo*², Giovanni Capretti^1,3, Gennaro Nappo^1,3, Panteleimon G. Takis^4,5,6, Alessandro Zerbi^1,3, Federica Marchesi^2,7, Nina Cortese²

¹Section of Pancreatic Surgery,Humanitas Clinical and Research Center-IRCCS, ²Department of Immunology and Inflammation,Humanitas Clinical and Research Center-IRCCS, ³Department of Biomedical Sciences,Humanitas University, ⁴Giotto Biotech S.R.L., ⁵Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction,Imperial College London, ⁶National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine,Imperial College London, ⁷Department of Medical Biotechnology and Translational Medicine,University of Milan

Journal (Cancer Research)

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Jing Zhang¹, Midory Thorikay¹, Gerard van der Zon¹, Maarten van Dinther¹, Peter ten Dijke¹

¹Oncode Institute and Department of Cell Chemical Biology,Leiden University Medical Center

Journal (Cancer Research)

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Lunpo Wu^1,2, Chenyang Ge³, Hongjuan Zheng⁴, Haiping Lin⁵, Wei Fu⁶, Jianfei Fu⁴

¹Department of Gastroenterology,Second Affiliated Hospital of Zhejiang University School of Medicine, ²Institute of Gastroenterology,Zhejiang University, ³Department of Colorectal Surgery, Afiliated Jinhua Hospital,Zhejiang University School of Medicine, ⁴Department of Medical Oncology, Affiliated Jinhua Hospital,Zhejiang University School of Medicine, ⁵Department of Hepatobiliary Pancreatic Surgery, Affiliated Jinhua Hospital,Zhejiang University School of Medicine, ⁶Division of Oncology,Johns Hopkins University School of Medicine

Journal (Cancer Research)

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans

Dharini van der Hoeven^1,2, Thuy Nhu L. Truong¹, Ali Naji¹, Sabita Thapa¹, John F. Hancock², Ransome van der Hoeven¹

¹Department of Diagnostic and Biomedical Sciences, School of Dentistry,University of Texas Health Science Center, ²Department of Integrative Biology and Pharmacology, McGovern Medical School,University of Texas Health Science Center

Journal (Cancer Research)

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Margaret A. Nagai-Singer¹, Alissa Hendricks-Wenger^1,2,3, Rebecca M. Brock^1,2, Holly A. Morrison¹, Juselyn D. Tupik¹, Sheryl Coutermarsh-Ott¹, Irving C. Allen^1,2,4

¹Department of Biomedical Sciences and Pathobiology,Virginia-Maryland College of Veterinary Medicine, ²Graduate Program in Translational Biology, Medicine and Health,Virginia Polytechnic Institute and State University, ³Department of Biomedical Engineering and Mechanics,Virginia Polytechnic Institute and State University, ⁴Department of Basic Science Education, Virginia Tech Carilion School of Medicine,Virginia Polytechnic Institute and State University

Journal (Cancer Research)

Isolation and Functional Assessment of Human Breast Cancer Stem Cells from Cell and Tissue Samples

Vasudeva Bhat^1,2, Cory Lefebvre^1,2, David Goodale¹, Mauricio Rodriguez-Torres^1,2, Alison L. Allan^1,2,3,4

¹London Regional Cancer Program, ²Department of Anatomy & Cell Biology,Western University, ³Department of Oncology,Western University, ⁴Lawson Health Research Institute

Journal (Cancer Research)

An Orthotopic Resectional Mouse Model of Pancreatic Cancer

Tony C. Y. Pang^1,2,4,5, Zhihong Xu^1,2, Alpha Raj Mekapogu^1,2, Srinivasa Pothula^1,2, Therese M. Becker³, David Goldstein¹, Romano C. Pirola^1,2, Jeremy S. Wilson^1,2, Minoti V. Apte^1,2

¹Pancreatic Research Group, South Western Sydney Clinical School,University of New South Wales, ²Ingham Institute for Applied Medical Research, ³Centre for Circulating Tumour Cell Diagnostics and Research,Ingham Institute for Applied Medical Research, ⁴Surgical Innovations Unit,Westmead Hospital, ⁵Westmead Clinical School,University of Sydney

Journal (Cancer Research)

In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells

Joan Repullés^1,2, Mariona Terradas^1,3,4, Gemma Fuster^5,6,7, Anna Genescà¹, Teresa Anglada¹

¹Department of Cell Biology, Physiology and Immunology,Universitat Autònoma de Barcelona, ²Optical Microscopy Core Facilities,IDIBELL, ³Hereditary Cancer Program, Catalan Institute of Oncology,IDIBELL, ⁴Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell),IDIBELL, ⁵New Therapeutic Strategies in Cancer Group. Department of Biochemistry and Molecular Biomedicine, School of Biology, Institute of Biomedicine,University of Barcelona (IBUB), ⁶Department of Biochemistry & Physiology, School of Pharmacy and Food Sciences,University of Barcelona, ⁷Department of Biosciences, Faculty of Sciences and Technology,University of Vic

Journal (Cancer Research)

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Nan Du^1,2, Jingqin Ma^1,2, Minjie Yang^1,2, Zihan Zhang^1,2, Zhiyuan Zheng^1,2, Wen Zhang*^1,2, Zhiping Yan*^1,2

¹Department of Interventional Radiology, Zhongshan Hospital,Fudan University, ²Shanghai Institution of Medical Imaging

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