Alkali Burn-Induced Corneal Neovascularization in Mice

Alkali Burn-Induced Corneal Neovascularization in Mice

June 30, 2023

Author Spotlight: Decoding Corneal Neovascularization with Alkali Burn Model for Future Therapeutic Strategies

Alkali Burn on the Mouse Cornea and OCT Imaging

Remya Ammassam Veettil¹, Wei Li¹, Stephen C. Pflugfelder¹, Douglas D. Koch¹

¹Cullen Eye Institute, Department of Ophthalmology,Baylor College of Medicine

Summary

This protocol focuses on alkali burn-induced corneal neovascularization in mice. The method generates a reproducible and controllable corneal disease model to study pathological angiogenesis and the associated molecular mechanisms and to test new pharmacological agents to prevent corneal neovascularization.

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