Alfonso Martinez Arias Department of Genetics University of Cambridge Biography Publications Institution JoVE Articles Alfonso Martinez Arias has not added a biography. If you are Alfonso Martinez Arias and would like to personalize this page please email our Author Liaison for assistance. Publications FGF/MAPK Signaling Sets the Switching Threshold of a Bistable Circuit Controlling Cell Fate Decisions in ES Cells Development (Cambridge, England). Oct, 2015 | Pubmed ID: 26511924 A Loss-of-function and H2B-Venus Transcriptional Reporter Allele for Gata6 in Mice BMC Developmental Biology. 2015 | Pubmed ID: 26498761 Inhibition of β-catenin-TCF1 Interaction Delays Differentiation of Mouse Embryonic Stem Cells The Journal of Cell Biology. Oct, 2015 | Pubmed ID: 26459597 Wnt/ß-catenin Signalling and the Dynamics of Fate Decisions in Early Mouse Embryos and Embryonic Stem (ES) Cells Seminars in Cell & Developmental Biology. Aug, 2015 | Pubmed ID: 26321498 Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells Stem Cells (Dayton, Ohio). Sep, 2015 | Pubmed ID: 26059426 Cell Dynamics and Gene Expression Control in Tissue Homeostasis and Development Molecular Systems Biology. Jan, 2015 | Pubmed ID: 25716053 Wnt/β-catenin and FGF Signalling Direct the Specification and Maintenance of a Neuromesodermal Axial Progenitor in Ensembles of Mouse Embryonic Stem Cells Development (Cambridge, England). Nov, 2014 | Pubmed ID: 25371361 Symmetry Breaking, Germ Layer Specification and Axial Organisation in Aggregates of Mouse Embryonic Stem Cells Development (Cambridge, England). Nov, 2014 | Pubmed ID: 25371360 Brachyury Cooperates with Wnt/β-catenin Signalling to Elicit Primitive-streak-like Behaviour in Differentiating Mouse Embryonic Stem Cells BMC Biology. 2014 | Pubmed ID: 25115237 An Interplay Between Extracellular Signalling and the Dynamics of the Exit from Pluripotency Drives Cell Fate Decisions in Mouse ES Cells Biology Open. 2014 | Pubmed ID: 24950969 Determining Protein Subcellular Localization in Mammalian Cell Culture with Biochemical Fractionation and ITRAQ 8-plex Quantification Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24791987 Contractile and Mechanical Properties of Epithelia with Perturbed Actomyosin Dynamics PloS One. 2014 | Pubmed ID: 24759936 Single Cell Lineage Analysis of Mouse Embryonic Stem Cells at the Exit from Pluripotency Biology Open. 2013 | Pubmed ID: 24167715 A Competitive Protein Interaction Network Buffers Oct4-mediated Differentiation to Promote Pluripotency in Embryonic Stem Cells Molecular Systems Biology. 2013 | Pubmed ID: 24104477 A Molecular Basis for Developmental Plasticity in Early Mammalian Embryos Development (Cambridge, England). Sep, 2013 | Pubmed ID: 23942513 A Membrane-associated β-catenin/Oct4 Complex Correlates with Ground-state Pluripotency in Mouse Embryonic Stem Cells Development (Cambridge, England). Mar, 2013 | Pubmed ID: 23444350 Activation of Notch in Lgd Mutant Cells Requires the Fusion of Late Endosomes with the Lysosome Journal of Cell Science. Jan, 2013 | Pubmed ID: 23178945 Interactions Between the Amnioserosa and the Epidermis Revealed by the Function of the U-shaped Gene Biology Open. Apr, 2012 | Pubmed ID: 23213425 Towards a Statistical Mechanics of Cell Fate Decisions Current Opinion in Genetics & Development. Dec, 2012 | Pubmed ID: 23200114 Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells Biophysical Journal. Nov, 2012 | Pubmed ID: 23200040 Cell Signalling Regulates Dynamics of Nanog Distribution in Embryonic Stem Cell Populations Journal of the Royal Society, Interface / the Royal Society. Oct, 2012 | Pubmed ID: 23054952 Correlations Between the Levels of Oct4 and Nanog As a Signature for Naïve Pluripotency in Mouse Embryonic Stem Cells Stem Cells (Dayton, Ohio). Dec, 2012 | Pubmed ID: 22969005 Drosophila Midgut Homeostasis Involves Neutral Competition Between Symmetrically Dividing Intestinal Stem Cells The EMBO Journal. May, 2012 | Pubmed ID: 22522699 Interplay Between Gene Expression Noise and Regulatory Network Architecture Trends in Genetics : TIG. May, 2012 | Pubmed ID: 22365642 The Structure of Wntch Signalling and the Resolution of Transition States in Development Seminars in Cell & Developmental Biology. Jun, 2012 | Pubmed ID: 22326376 Dissecting Ensemble Networks in ES Cell Populations Reveals Micro-heterogeneity Underlying Pluripotency Molecular BioSystems. Mar, 2012 | Pubmed ID: 22222461 Wnt-Notch Signalling: an Integrated Mechanism Regulating Transitions Between Cell States BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2012 | Pubmed ID: 22215536 Patterned Cell Adhesion Associated with Tissue Deformations During Dorsal Closure in Drosophila PloS One. 2011 | Pubmed ID: 22076130 Gene Expression Heterogeneities in Embryonic Stem Cell Populations: Origin and Function Current Opinion in Cell Biology. Dec, 2011 | Pubmed ID: 21982544 Probing the Druggability of Protein-protein Interactions: Targeting the Notch1 Receptor Ankyrin Domain Using a Fragment-based Approach Biochemical Society Transactions. Oct, 2011 | Pubmed ID: 21936810 Endocytic and Recycling Endosomes Modulate Cell Shape Changes and Tissue Behaviour During Morphogenesis in Drosophila PloS One. 2011 | Pubmed ID: 21533196 Modulation of the Ligand-independent Traffic of Notch by Axin and Apc Contributes to the Activation of Armadillo in Drosophila Development (Cambridge, England). Apr, 2011 | Pubmed ID: 21389052 Cytoskeletal Dynamics and Supracellular Organisation of Cell Shape Fluctuations During Dorsal Closure Development (Cambridge, England). Aug, 2010 | Pubmed ID: 20663818 Wingless Modulates the Ligand Independent Traffic of Notch Through Dishevelled Fly. Jul-Sep, 2010 | Pubmed ID: 20495361 A Role of Receptor Notch in Ligand Cis-inhibition in Drosophila Current Biology : CB. Mar, 2010 | Pubmed ID: 20226663 Mechanisms of Ligand-mediated Inhibition in Notch Signaling Activity in Drosophila Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2010 | Pubmed ID: 20063416 A Perspective on the Development of Genetics in Spain During the XX Century The International Journal of Developmental Biology. 2009 | Pubmed ID: 19924624 The Structural and Functional Determinants of the Axin and Dishevelled DIX Domains BMC Structural Biology. 2009 | Pubmed ID: 19909509 Ligand-independent Traffic of Notch Buffers Activated Armadillo in Drosophila PLoS Biology. Aug, 2009 | Pubmed ID: 19668359 Origin and Function of Fluctuations in Cell Behaviour and the Emergence of Patterns Seminars in Cell & Developmental Biology. Sep, 2009 | Pubmed ID: 19665568 Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells PLoS Biology. Jul, 2009 | Pubmed ID: 19582141 Mechanical Control of Global Cell Behaviour During Dorsal Closure in Drosophila Development (Cambridge, England). Jun, 2009 | Pubmed ID: 19403661 Getting the Measure of Positional Information PLoS Biology. Mar, 2009 | Pubmed ID: 19338391 Mapping Organelle Proteins and Protein Complexes in Drosophila Melanogaster Journal of Proteome Research. Jun, 2009 | Pubmed ID: 19317464 Flamingo Regulates Epiboly and Convergence/extension Movements Through Cell Cohesive and Signalling Functions During Zebrafish Gastrulation Development (Cambridge, England). Feb, 2009 | Pubmed ID: 19091770 The Drosophila STIM1 Orthologue, DSTIM, Has Roles in Cell Fate Specification and Tissue Patterning BMC Developmental Biology. 2008 | Pubmed ID: 18950512 Wingless Signalling Alters the Levels, Subcellular Distribution and Dynamics of Armadillo and E-cadherin in Third Instar Larval Wing Imaginal Discs PloS One. 2008 | Pubmed ID: 18682750 Drosophila Melanogaster and the Development of Biology in the 20th Century Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18641938 Wnt/Notch Signalling and Information Processing During Development Development (Cambridge, England). Feb, 2008 | Pubmed ID: 18192283 Dpp Signalling Orchestrates Dorsal Closure by Regulating Cell Shape Changes Both in the Amnioserosa and in the Epidermis Mechanisms of Development. Nov-Dec, 2007 | Pubmed ID: 17950580 Requirements for Adherens Junction Components in the Interaction Between Epithelial Tissues During Dorsal Closure in Drosophila Journal of Cell Science. Sep, 2007 | Pubmed ID: 17878238 Cell and Molecular Biology of Notch The Journal of Endocrinology. Sep, 2007 | Pubmed ID: 17761886 Notch Signaling Pathway Science's STKE : Signal Transduction Knowledge Environment. Dec, 2006 | Pubmed ID: 17148788 Notch, a Universal Arbiter of Cell Fate Decisions Science (New York, N.Y.). Dec, 2006 | Pubmed ID: 17138893 High-throughput Localization of Organelle Proteins by Mass Spectrometry: a Quantum Leap for Cell Biology BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Aug, 2006 | Pubmed ID: 16927390 Notch Synergizes with Axin to Regulate the Activity of Armadillo in Drosophila Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2006 | Pubmed ID: 16881048 Notch Receptor Encodes Two Structurally Separable Functions in Drosophila: a Genetic Analysis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2006 | Pubmed ID: 16534797 Filtering Transcriptional Noise During Development: Concepts and Mechanisms Nature Reviews. Genetics. Jan, 2006 | Pubmed ID: 16369570 Cell Signaling. Frizzled at the Cutting Edge of the Synapse Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16311322 High-resolution Crystal Structure of the Human Notch 1 Ankyrin Domain The Biochemical Journal. Nov, 2005 | Pubmed ID: 16011479 Notch Modulates Wnt Signalling by Associating with Armadillo/beta-catenin and Regulating Its Transcriptional Activity Development (Cambridge, England). Apr, 2005 | Pubmed ID: 15772135 Armadillo/beta-catenin-dependent Wnt Signalling is Required for the Polarisation of Epidermal Cells During Dorsal Closure in Drosophila Development (Cambridge, England). Jul, 2004 | Pubmed ID: 15226252 Building and Engineering Organisms: the Cellular Interface Mechanisms of Development. Nov, 2003 | Pubmed ID: 14623433 Wnts As Morphogens? The View from the Wing of Drosophila Nature Reviews. Molecular Cell Biology. Apr, 2003 | Pubmed ID: 12671654 Planar Polarity and Actin Dynamics in the Epidermis of Drosophila Nature Cell Biology. Dec, 2002 | Pubmed ID: 12447392 CSL-independent Notch Signalling: a Checkpoint in Cell Fate Decisions During Development? Current Opinion in Genetics & Development. Oct, 2002 | Pubmed ID: 12200157 A New Dawn for an Old Connection: Development Meets the Cell Trends in Cell Biology. Jul, 2002 | Pubmed ID: 12185848 Dynamic Analysis of Actin Cable Function During Drosophila Dorsal Closure Current Biology : CB. Jul, 2002 | Pubmed ID: 12176336 New Alleles of Notch Draw a Blueprint for Multifunctionality Trends in Genetics : TIG. Apr, 2002 | Pubmed ID: 11932008 The Antennapedia Gene is Required and Expressed in Parasegments 4 and 5 of the Drosophila Embryo The EMBO Journal. Jan, 1986 | Pubmed ID: 16453662 Fare Embriyonik Kök Hücre Agregaların Üretimi Simetri Kırma, Polarizasyon ve Acil Toplu Davranış göster o Peter Baillie-Johnson1, Susanne Carina van den Brink1,2, Tina Balayo1, David Andrew Turner1, Alfonso Martinez Arias1 1Department of Genetics, University of Cambridge, 2Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences Biología del desarrollo
Fare Embriyonik Kök Hücre Agregaların Üretimi Simetri Kırma, Polarizasyon ve Acil Toplu Davranış göster o Peter Baillie-Johnson1, Susanne Carina van den Brink1,2, Tina Balayo1, David Andrew Turner1, Alfonso Martinez Arias1 1Department of Genetics, University of Cambridge, 2Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences Biología del desarrollo