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Sıçanlarda Tibial Nöroma Transpozisyon Modelinde Cerrahi ve Davranışsal Test
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JoVE Journal Neurowissenschaften
Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats
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Sıçanlarda Tibial Nöroma Transpozisyon Modelinde Cerrahi ve Davranışsal Test

1,544 Views

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07:23 min

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January 06, 2023

DOI:

10.3791/64659-v

DOI:
10.3791/64659-v

•

07:23 min
January 06, 2023

•

18 Views
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1Department of Plastic and Reconstructive Surgery,University Medical Center Utrecht, Utrecht University, 2Axogen, 3Center for Translational Immunology,University Medical Center Utrecht, Utrecht University

Summary

Automatically generated

Bu protokol, tibial sinirin lezyonunu ve ardından proksimal sinir ucunun subkutan pretibial veya lateral pozisyona doğru transpozisyonunu gerektiren tibial nöroma transpozisyon modelini tanımlar. Nöroma ağrısı ve plantar hiperaljezinin davranışsal testleri, Von Frey monofilamentleri kullanılarak ölçülür.

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Cite this Article

Brakkee, E. M., DeVinney, E., Eijkelkamp, N., Coert, J. H. Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats. J. Vis. Exp. (191), e64659, doi:10.3791/64659 (2023).

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