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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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04:39 min
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March 17, 2023
DOI:
1Thyroid and Parathyroid Surgery Center,West China Hospital of Sichuan University, 2The Laboratory of Thyroid and Parathyroid Disease,West China Hospital of Sichuan University, 3State Key Laboratory of Biotherapy and Cancer Center, West China Hospital,Sichuan University and Collaborative Innovation Center
Summary
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Several types of animal models of Hashimoto's thyroiditis have been established, as has spontaneous autoimmune thyroiditis in the NOD mouse. H-2h4 mice are a simple and reliable model for HT induction. This article describes this approach and evaluates the pathological process for a better understanding of the SAT murine model.
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Cite this Article
Qian, Y., He, L., Su, A., Hu, Y., Zhu, J. Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model. J. Vis. Exp. (193), e64609, doi:10.3791/64609 (2023).
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