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Journal / Medicine / 肠系膜上动脉闭塞的肠缺血再灌注损伤的啮齿动物模型…
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肠系膜上动脉闭塞的肠缺血再灌注损伤的啮齿动物模型
 
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肠系膜上动脉闭塞的肠缺血再灌注损伤的啮齿动物模型

Article DOI: 10.3791/64314-v • 06:29 min • October 20th, 2023
October 20th, 2023 •
1,2, 1, 1, 3
1Animal Surgery and Resources Core, National Heart, Lung, and Blood Institute, National Institutes of Health, 2College of Veterinary Medicine, Mississippi State University, 3Division of Veterinary Resources, Office of Research Services, National Institutes of Health

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我们描述了如何生成啮齿动物肠缺血再灌注损伤 （IRI） 的广泛使用的手术模型。该手术包括闭塞肠系膜上动脉，然后恢复血流。该模型可用于调查兽医和人类医学中肠道 IRI 闭塞原因的研究。

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肠缺血再灌注损伤，啮齿动物模型，肠系膜上动脉闭塞，胃扩张扭转，肠系膜扭转，绞痛，自由基形成，氧气再引入，预后不良，体内模型，异氟醚麻醉，可重复损伤，组织病理学，小肠，结肠，肝脏，肾脏
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