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Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
Kapitel
- 00:05Introduction
- 00:53Formaldehyde Fixation
- 07:54Results: Capture Hi-C, 5C, and Hi-C Interaction Maps across the 3 Mb and 1 Mb Captured Region
- 09:05Conclusion
This protocol describes the Capture Hi-C method used to characterize the 3D organization of megabased-sized targeted genomic regions at high-resolution, including boundaries of topologically associating domains (TADs) and long-range chromatin interactions between regulatory and other DNA sequence elements.
