Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
2,751 Views
•
04:38 min
•
July 28, 2022
DOI:
Summary
Automatically generated
Contiguous bisaziridines containing non-activated and activated aziridines were synthesized by asymmetric organocatalytic aziridinations and then subjected to chemoselective ring-opening reactions under acidic or basic conditions. The non-activated aziridine ring opens with less reactive nucleophiles under acidic conditions, whereas the activated aziridine ring opens with more reactive nucleophiles under basic conditions.
Read Article
Cite this Article
Lee, Y., Byeon, H., Ha, H., Yang, J. W. Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions. J. Vis. Exp. (185), e64019, doi:10.3791/64019 (2022).
Copy