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A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
JoVE Journal
Verhalten
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JoVE Journal Verhalten
A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
DOI:

08:05 min

March 23, 2022

, ,

Kapitel

  • 00:04Introduction
  • 00:43Behavioral Procedure
  • 06:39Results: Acute Food Deprivation-Induced Relapse to Heroin Seeking Abstinence in the Rats
  • 07:27Conclusion

Summary

Automatische Übersetzung

A procedure that demonstrates a robust acute food deprivation-induced relapse to heroin seeking after punishment-imposed abstinence is described. A punishment-imposed abstinence model was successfully implemented using the seek and take chain schedule for heroin self-administration. Heroin-seeking tests are then performed following 24 h of food-deprivation stress.

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