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Measurement of Oxygen Consumption Rate in Acute Striatal Slices from Adult Mice
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Measurement of Oxygen Consumption Rate in Acute Striatal Slices from Adult Mice
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07:41 min
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June 08, 2022
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Oxygen consumption rate (OCR) is a common proxy for mitochondrial function and can be used to study different disease models. We developed a new method using a Seahorse XF analyzer to directly measure the OCR in acute striatal slices from adult mice that is more physiologically relevant than other methods.
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Zhi, L., Zhao, J., Jaffe, D., Chen, Y., Wang, N., Qin, Q., Seifert, E. L., Li, C., Zhang, H. Measurement of Oxygen Consumption Rate in Acute Striatal Slices from Adult Mice. J. Vis. Exp. (184), e63379, doi:10.3791/63379 (2022).
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