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果蝇细胞中的核内高C
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JoVE Journal Genetik
In-Nucleus Hi-C in Drosophila Cells
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果蝇细胞中的核内高C

3,830 Views

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11:58 min

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September 15, 2021

DOI:

10.3791/62106-v

DOI:
10.3791/62106-v

•

11:58 min
September 15, 2021

•

9 Views
, , ,
1Departamento de Genética Molecular, Instituto de Fisiología Celular,Universidad Nacional Autónoma de México

Summary

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基因组在核空间中组织成不同的结构，可以通过染色体构象捕获技术揭示出来。核内Hi-C方法提供了在果蝇细胞系中全基因组的染色质相互作用集合，生成接触图，可以在限制片段水平下以兆基分辨率进行探索。

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Cite this Article

Esquivel-López, A., Arzate-Mejía, R., Pérez-Molina, R., Furlan-Magaril, M. In-Nucleus Hi-C in Drosophila Cells. J. Vis. Exp. (175), e62106, doi:10.3791/62106 (2021).

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