/
/
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
4,868 Views
•
14:48 min
•
March 21, 2021
DOI:
Summary
Automatically generated
Combined ozone and bacterial endotoxin exposed mice show wide-spread cell death, including that of neutrophils. We observed cellular adaptations such as disruption of cytoskeletal lamellipodia, increased cellular expression of complex V ATP synthase subunit β and angiostatin in broncho-alveolar lavage, suppression of the lung immune response and delayed neutrophil recruitment.
Read Article
Cite this Article
Duda, J. A. B., Kaur, M., Aulakh, G. K. Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury. J. Vis. Exp. (169), e62097, doi:10.3791/62097 (2021).
Copy