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Study of Protein Dynamics via Neutron Spin Echo Spectroscopy
Kapitel
- 00:04Introduction
- 01:17Measurement of NSE
- 03:58NSE Data Reduction
- 05:05NSE Data Fitting
- 05:33Results: NSE Relaxation Spectra for IgG and MBP Proteins
- 06:39Conclusion
The present protocol describes methods for investigating the structure and dynamics of two model proteins that have an important role in human health. The technique combines bench-top biophysical characterization with neutron spin echo spectroscopy to access the dynamics at time and length scales relevant for protein interdomain motions.
