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Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
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Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
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08:44 min
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May 30, 2020
DOI:
1Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine,University of Texas Health San Antonio, 2Department of Clinical Laboratory Sciences, College of Applied Medical Sciences,Jouf University, 3Department of Otolaryngology-Head and Neck Surgery,Xiangya Hospital, Central South University
Summary
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Environmental allergens such as house dust mites (HDM) often contain microbial substances that activate innate immune responses to regulate allergic inflammation. The protocol presented here demonstrates the identification of dsRNA species in HDM allergens and characterization of their immunogenic activities in modulating eosinophilic lung inflammation.
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Alanazi, H. H., She, L., Li, X. Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation. J. Vis. Exp. (159), e61183, doi:10.3791/61183 (2020).
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