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Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
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JoVE Journal Neurowissenschaften
Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

11,289 Views

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09:54 min

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May 10, 2019

DOI:

10.3791/59189-v

DOI:
10.3791/59189-v

•

09:54 min
May 10, 2019

•

8 Views
, , , , , , , , ,
1Department of Otolaryngology-Head and Neck Surgery, Beijing Friendship Hospital,Capital Medical University, 2Department of Otology,Shengjing Hospital of China Medical University

Summary

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This manuscript describes an experimental protocol for evaluating the morphological characteristics and functional status of ribbon synapses in normal mice. The present model is also suitable for noise-induced and age-related cochlear synaptopathy-restricted models. The correlative results of previous mouse studies are also discussed.

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Yu, S., Du, Z., Song, Q., Qu, T., Qi, Y., Xiong, W., He, L., Wei, W., Gong, S., Liu, K. Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea. J. Vis. Exp. (147), e59189, doi:10.3791/59189 (2019).

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