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Expansion of Two-dimension Electrospun Nanofiber Mats into Three-dimension Scaffolds
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January 07, 2019
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This article demonstrates the technique of expanding a traditional, two-dimension (2D) electrospun nanofiber mat into a three-dimension (3D) scaffold through the depressurization of subcritical CO2 fluid. These augmented scaffolds are 3D, closely mimic cellular nanotopographic cues, and preserve the functions of biologic molecules encapsulated within the nanofibers.
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Keit, E., Chen, S., Wang, H., Xie, J. Expansion of Two-dimension Electrospun Nanofiber Mats into Three-dimension Scaffolds. J. Vis. Exp. (143), e58918, doi:10.3791/58918 (2019).
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