High-intensity training in hypoxia is a protocol that has been proven to induce vascular adaptations potentially beneficial in some patients and to improve athletes' repeated sprint ability. Here, we test the feasibility of training mice using that protocol and identify those vascular adaptations using ex vivo vascular function assessment.
Lavier, J., Beaumann, M., Ménetrey, S., Mazzolai, L., Peyter, A., Pellegrin, M., Millet, G. P. Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice. J. Vis. Exp. (145), e58708, doi:10.3791/58708 (2019).