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10:31 min
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October 25, 2018
DOI:
1Janssen R&D, 2Department of Microbiology and Immunology,University of North Carolina, 3UNC Food Allergy Initiative,University of North Carolina, 4Department of Pediatrics,University of North Carolina, 5Department of Chemistry,University of Alberta, 6Department of Molecular Medicine,Scripps Research Institute, 7Department of Medical Microbiology and Immunology,University of Alberta
Summary
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描述了抗原脂质体纳米粒子的制备及其在体外和体内刺激 B 细胞活化的作用。一致和稳健的抗体反应导致了一个新的花生过敏模型的发展。抗原脂质体的生成协议可以扩展到不同的抗原和免疫模型。
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Cite this Article
Bednar, K. J., Hardy, L., Smeekens, J., Raghuwanshi, D., Duan, S., Kulis, M. D., Macauley, M. S. Antigenic Liposomes for Generation of Disease-specific Antibodies. J. Vis. Exp. (140), e58285, doi:10.3791/58285 (2018).
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