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Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice
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Medizin
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JoVE Journal Medizin
Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice

Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice

17,045 Views

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06:59 min

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January 23, 2019

DOI:

10.3791/58191-v

DOI:
10.3791/58191-v

•

06:59 min
January 23, 2019

•

19 Views
, , ,
1Department of Neuroscience, Psychology and Behaviour,University of Leicester, 2Preclinical Imaging Facility, Core Biotechnology Services,University of Leicester, 3School of Psychology,University of Nottingham

Summary

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Intraluminal filament occlusion of the middle cerebral artery is the most frequently used in vivo model of experimental stroke in rodents. An alternative surgical approach to allow common carotid artery repair is performed here, which allows the reperfusion of the common carotid artery and a full reperfusion to the middle cerebral artery territory.

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Cite this Article

Trotman-Lucas, M., Kelly, M. E., Janus, J., Gibson, C. L. Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice. J. Vis. Exp. (143), e58191, doi:10.3791/58191 (2019).

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